Posted: 16:00, 18 August 2022 | Updated: 17:16, 18 August 2022
Scientists have discovered dozens of genes closely linked to autism, which could be a breakthrough.
Researchers hope the more than 70 genetic variants could pave the way for new tests and treatments for the condition.
Autism and related conditions such as Asperger’s affect more than one in 100 British children and one in 70 American young people — ten times more than 30 years ago.
Despite the rise, the condition is still poorly understood and diagnosis can be time-consuming and stressful for patients and their families.
Families are often forced to attend multiple hospital appointments and children undergo various psychological tests.
While medication can be given to control symptoms such as aggression or hyperactivity, there is no cure.
In the largest study of its kind, US researchers examined the DNA of 150,000 participants, 20,000 of whom had been diagnosed with autism.
They identified 72 genes “very strongly” associated with the condition and hundreds more with looser associations.
Scientists are one step closer to solving the puzzle of autism after discovering more than a hundred new genes linked to the condition
It is hoped that the latest study, published in Nature Genetics, will help future research teams narrow their focus.
Study co-author Dr Joseph Buxbaum, director of the Seaver Autism Center for Research and Treatment at Mount Sinai in New York, said: “We know that many genes, when mutated, contribute to autism.
“In this unprecedented study, we were able to bring together many types of mutations in a wide range of samples to gain a much richer sense of the genes and genetic architecture involved in autism.
“This is important as we now have more knowledge about the biology of the brain changes that underlie autism and more potential targets for treatment.”
He said a “precision medicine approach” to autism based on a person’s genes will likely be needed.
And people should be genetically screened for autism to help develop new drugs that “benefit families and individuals at risk for autism spectrum disorder,” Dr. Buxbaum said.
“The more we can advance treatment, based on the targets identified in these genetic findings, the more people we have the potential to help, which could have a major impact on tackling autism and developmental delay worldwide,” he added. .
His team gathered data from autism research initiatives such as the Autism Sequencing Consortium, as well as the Massachusetts Institute of Technology and Harvard.
They looked at the genomes of about 150,000 people, 20,627 of whom had autism.
In addition to the 72 genes that appear to be behind autism, they identified another 250 that are also linked to the condition.
What are the signs of autism?
Signs of autism in young children include:
It doesn’t live up to their name Avoiding eye contact Don’t smile when you smile at them They get very upset if they don’t like a certain taste, smell or sound Repetitive movements, such as waving their arms, wiggling their fingers, or moving their body He doesn’t talk as much as other kids Repeating the same phrases
Signs of autism in older children include:
He doesn’t seem to understand what other people are thinking or feeling They have trouble saying how they feel You like a strict daily routine and get very upset if it changes Having a very strong interest in certain subjects or activities You get very upset if you ask them to do something They have difficulty making friends or prefer to be alone Taking things too literally – for example, they may not understand phrases like ‘break your leg’
Common signs of autism in adults include:
I have trouble understanding what other people are thinking or feeling Be very anxious about social situations You have trouble making friends or prefer to be alone I come across as rude, rude, or uninterested to others without meaning to It’s hard to tell how you feel Taking things too literally – for example, you may not understand sarcasm or phrases like ‘break your leg’ Having the same routine every day and getting very anxious if it changes
Source: NHS
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title: “Autism Breakthrough As Scientists Discover 70 Genes Strongly Linked To Condition Klmat” ShowToc: true date: “2022-11-22” author: “Teresa Cummings”
Posted: 16:00, 18 August 2022 | Updated: 17:16, 18 August 2022
Scientists have discovered dozens of genes closely linked to autism, which could be a breakthrough.
Researchers hope the more than 70 genetic variants could pave the way for new tests and treatments for the condition.
Autism and related conditions such as Asperger’s affect more than one in 100 British children and one in 70 American young people — ten times more than 30 years ago.
Despite the rise, the condition is still poorly understood and diagnosis can be time-consuming and stressful for patients and their families.
Families are often forced to attend multiple hospital appointments and children undergo various psychological tests.
While medication can be given to control symptoms such as aggression or hyperactivity, there is no cure.
In the largest study of its kind, US researchers examined the DNA of 150,000 participants, 20,000 of whom had been diagnosed with autism.
They identified 72 genes “very strongly” associated with the condition and hundreds more with looser associations.
Scientists are one step closer to solving the puzzle of autism after discovering more than a hundred new genes linked to the condition
It is hoped that the latest study, published in Nature Genetics, will help future research teams narrow their focus.
Study co-author Dr Joseph Buxbaum, director of the Seaver Autism Center for Research and Treatment at Mount Sinai in New York, said: “We know that many genes, when mutated, contribute to autism.
“In this unprecedented study, we were able to bring together many types of mutations in a wide range of samples to gain a much richer sense of the genes and genetic architecture involved in autism.
“This is important as we now have more knowledge about the biology of the brain changes that underlie autism and more potential targets for treatment.”
He said a “precision medicine approach” to autism based on a person’s genes will likely be needed.
And people should be genetically screened for autism to help develop new drugs that “benefit families and individuals at risk for autism spectrum disorder,” Dr. Buxbaum said.
“The more we can advance treatment, based on the targets identified in these genetic findings, the more people we have the potential to help, which could have a major impact on tackling autism and developmental delay worldwide,” he added. .
His team gathered data from autism research initiatives such as the Autism Sequencing Consortium, as well as the Massachusetts Institute of Technology and Harvard.
They looked at the genomes of about 150,000 people, 20,627 of whom had autism.
In addition to the 72 genes that appear to be behind autism, they identified another 250 that are also linked to the condition.
What are the signs of autism?
Signs of autism in young children include:
It doesn’t live up to their name Avoiding eye contact Don’t smile when you smile at them They get very upset if they don’t like a certain taste, smell or sound Repetitive movements, such as waving their arms, wiggling their fingers, or moving their body He doesn’t talk as much as other kids Repeating the same phrases
Signs of autism in older children include:
He doesn’t seem to understand what other people are thinking or feeling They have trouble saying how they feel You like a strict daily routine and get very upset if it changes Having a very strong interest in certain subjects or activities You get very upset if you ask them to do something They have difficulty making friends or prefer to be alone Taking things too literally – for example, they may not understand phrases like ‘break your leg’
Common signs of autism in adults include:
I have trouble understanding what other people are thinking or feeling Be very anxious about social situations You have trouble making friends or prefer to be alone I come across as rude, rude, or uninterested to others without meaning to It’s hard to tell how you feel Taking things too literally – for example, you may not understand sarcasm or phrases like ‘break your leg’ Having the same routine every day and getting very anxious if it changes
Source: NHS
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title: “Autism Breakthrough As Scientists Discover 70 Genes Strongly Linked To Condition Klmat” ShowToc: true date: “2022-12-16” author: “Margo Spivey”
Posted: 16:00, 18 August 2022 | Updated: 17:16, 18 August 2022
Scientists have discovered dozens of genes closely linked to autism, which could be a breakthrough.
Researchers hope the more than 70 genetic variants could pave the way for new tests and treatments for the condition.
Autism and related conditions such as Asperger’s affect more than one in 100 British children and one in 70 American young people — ten times more than 30 years ago.
Despite the rise, the condition is still poorly understood and diagnosis can be time-consuming and stressful for patients and their families.
Families are often forced to attend multiple hospital appointments and children undergo various psychological tests.
While medication can be given to control symptoms such as aggression or hyperactivity, there is no cure.
In the largest study of its kind, US researchers examined the DNA of 150,000 participants, 20,000 of whom had been diagnosed with autism.
They identified 72 genes “very strongly” associated with the condition and hundreds more with looser associations.
Scientists are one step closer to solving the puzzle of autism after discovering more than a hundred new genes linked to the condition
It is hoped that the latest study, published in Nature Genetics, will help future research teams narrow their focus.
Study co-author Dr Joseph Buxbaum, director of the Seaver Autism Center for Research and Treatment at Mount Sinai in New York, said: “We know that many genes, when mutated, contribute to autism.
“In this unprecedented study, we were able to bring together many types of mutations in a wide range of samples to gain a much richer sense of the genes and genetic architecture involved in autism.
“This is important as we now have more knowledge about the biology of the brain changes that underlie autism and more potential targets for treatment.”
He said a “precision medicine approach” to autism based on a person’s genes will likely be needed.
And people should be genetically screened for autism to help develop new drugs that “benefit families and individuals at risk for autism spectrum disorder,” Dr. Buxbaum said.
“The more we can advance treatment, based on the targets identified in these genetic findings, the more people we have the potential to help, which could have a major impact on tackling autism and developmental delay worldwide,” he added. .
His team gathered data from autism research initiatives such as the Autism Sequencing Consortium, as well as the Massachusetts Institute of Technology and Harvard.
They looked at the genomes of about 150,000 people, 20,627 of whom had autism.
In addition to the 72 genes that appear to be behind autism, they identified another 250 that are also linked to the condition.
What are the signs of autism?
Signs of autism in young children include:
It doesn’t live up to their name Avoiding eye contact Don’t smile when you smile at them They get very upset if they don’t like a certain taste, smell or sound Repetitive movements, such as waving their arms, wiggling their fingers, or moving their body He doesn’t talk as much as other kids Repeating the same phrases
Signs of autism in older children include:
He doesn’t seem to understand what other people are thinking or feeling They have trouble saying how they feel You like a strict daily routine and get very upset if it changes Having a very strong interest in certain subjects or activities You get very upset if you ask them to do something They have difficulty making friends or prefer to be alone Taking things too literally – for example, they may not understand phrases like ‘break your leg’
Common signs of autism in adults include:
I have trouble understanding what other people are thinking or feeling Be very anxious about social situations You have trouble making friends or prefer to be alone I come across as rude, rude, or uninterested to others without meaning to It’s hard to tell how you feel Taking things too literally – for example, you may not understand sarcasm or phrases like ‘break your leg’ Having the same routine every day and getting very anxious if it changes
Source: NHS
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title: “Autism Breakthrough As Scientists Discover 70 Genes Strongly Linked To Condition Klmat” ShowToc: true date: “2022-12-12” author: “Sheila Gonsalves”
Posted: 16:00, 18 August 2022 | Updated: 17:16, 18 August 2022
Scientists have discovered dozens of genes closely linked to autism, which could be a breakthrough.
Researchers hope the more than 70 genetic variants could pave the way for new tests and treatments for the condition.
Autism and related conditions such as Asperger’s affect more than one in 100 British children and one in 70 American young people — ten times more than 30 years ago.
Despite the rise, the condition is still poorly understood and diagnosis can be time-consuming and stressful for patients and their families.
Families are often forced to attend multiple hospital appointments and children undergo various psychological tests.
While medication can be given to control symptoms such as aggression or hyperactivity, there is no cure.
In the largest study of its kind, US researchers examined the DNA of 150,000 participants, 20,000 of whom had been diagnosed with autism.
They identified 72 genes “very strongly” associated with the condition and hundreds more with looser associations.
Scientists are one step closer to solving the puzzle of autism after discovering more than a hundred new genes linked to the condition
It is hoped that the latest study, published in Nature Genetics, will help future research teams narrow their focus.
Study co-author Dr Joseph Buxbaum, director of the Seaver Autism Center for Research and Treatment at Mount Sinai in New York, said: “We know that many genes, when mutated, contribute to autism.
“In this unprecedented study, we were able to bring together many types of mutations in a wide range of samples to gain a much richer sense of the genes and genetic architecture involved in autism.
“This is important as we now have more knowledge about the biology of the brain changes that underlie autism and more potential targets for treatment.”
He said a “precision medicine approach” to autism based on a person’s genes will likely be needed.
And people should be genetically screened for autism to help develop new drugs that “benefit families and individuals at risk for autism spectrum disorder,” Dr. Buxbaum said.
“The more we can advance treatment, based on the targets identified in these genetic findings, the more people we have the potential to help, which could have a major impact on tackling autism and developmental delay worldwide,” he added. .
His team gathered data from autism research initiatives such as the Autism Sequencing Consortium, as well as the Massachusetts Institute of Technology and Harvard.
They looked at the genomes of about 150,000 people, 20,627 of whom had autism.
In addition to the 72 genes that appear to be behind autism, they identified another 250 that are also linked to the condition.
What are the signs of autism?
Signs of autism in young children include:
It doesn’t live up to their name Avoiding eye contact Don’t smile when you smile at them They get very upset if they don’t like a certain taste, smell or sound Repetitive movements, such as waving their arms, wiggling their fingers, or moving their body He doesn’t talk as much as other kids Repeating the same phrases
Signs of autism in older children include:
He doesn’t seem to understand what other people are thinking or feeling They have trouble saying how they feel You like a strict daily routine and get very upset if it changes Having a very strong interest in certain subjects or activities You get very upset if you ask them to do something They have difficulty making friends or prefer to be alone Taking things too literally – for example, they may not understand phrases like ‘break your leg’
Common signs of autism in adults include:
I have trouble understanding what other people are thinking or feeling Be very anxious about social situations You have trouble making friends or prefer to be alone I come across as rude, rude, or uninterested to others without meaning to It’s hard to tell how you feel Taking things too literally – for example, you may not understand sarcasm or phrases like ‘break your leg’ Having the same routine every day and getting very anxious if it changes
Source: NHS
Share or comment on this article:
title: “Autism Breakthrough As Scientists Discover 70 Genes Strongly Linked To Condition Klmat” ShowToc: true date: “2022-11-13” author: “Mike Powell”
Posted: 16:00, 18 August 2022 | Updated: 17:16, 18 August 2022
Scientists have discovered dozens of genes closely linked to autism, which could be a breakthrough.
Researchers hope the more than 70 genetic variants could pave the way for new tests and treatments for the condition.
Autism and related conditions such as Asperger’s affect more than one in 100 British children and one in 70 American young people — ten times more than 30 years ago.
Despite the rise, the condition is still poorly understood and diagnosis can be time-consuming and stressful for patients and their families.
Families are often forced to attend multiple hospital appointments and children undergo various psychological tests.
While medication can be given to control symptoms such as aggression or hyperactivity, there is no cure.
In the largest study of its kind, US researchers examined the DNA of 150,000 participants, 20,000 of whom had been diagnosed with autism.
They identified 72 genes “very strongly” associated with the condition and hundreds more with looser associations.
Scientists are one step closer to solving the puzzle of autism after discovering more than a hundred new genes linked to the condition
It is hoped that the latest study, published in Nature Genetics, will help future research teams narrow their focus.
Study co-author Dr Joseph Buxbaum, director of the Seaver Autism Center for Research and Treatment at Mount Sinai in New York, said: “We know that many genes, when mutated, contribute to autism.
“In this unprecedented study, we were able to bring together many types of mutations in a wide range of samples to gain a much richer sense of the genes and genetic architecture involved in autism.
“This is important as we now have more knowledge about the biology of the brain changes that underlie autism and more potential targets for treatment.”
He said a “precision medicine approach” to autism based on a person’s genes will likely be needed.
And people should be genetically screened for autism to help develop new drugs that “benefit families and individuals at risk for autism spectrum disorder,” Dr. Buxbaum said.
“The more we can advance treatment, based on the targets identified in these genetic findings, the more people we have the potential to help, which could have a major impact on tackling autism and developmental delay worldwide,” he added. .
His team gathered data from autism research initiatives such as the Autism Sequencing Consortium, as well as the Massachusetts Institute of Technology and Harvard.
They looked at the genomes of about 150,000 people, 20,627 of whom had autism.
In addition to the 72 genes that appear to be behind autism, they identified another 250 that are also linked to the condition.
What are the signs of autism?
Signs of autism in young children include:
It doesn’t live up to their name Avoiding eye contact Don’t smile when you smile at them They get very upset if they don’t like a certain taste, smell or sound Repetitive movements, such as waving their arms, wiggling their fingers, or moving their body He doesn’t talk as much as other kids Repeating the same phrases
Signs of autism in older children include:
He doesn’t seem to understand what other people are thinking or feeling They have trouble saying how they feel You like a strict daily routine and get very upset if it changes Having a very strong interest in certain subjects or activities You get very upset if you ask them to do something They have difficulty making friends or prefer to be alone Taking things too literally – for example, they may not understand phrases like ‘break your leg’
Common signs of autism in adults include:
I have trouble understanding what other people are thinking or feeling Be very anxious about social situations You have trouble making friends or prefer to be alone I come across as rude, rude, or uninterested to others without meaning to It’s hard to tell how you feel Taking things too literally – for example, you may not understand sarcasm or phrases like ‘break your leg’ Having the same routine every day and getting very anxious if it changes
Source: NHS
